Cell Extracellular Matrix and EMT

EMT is a biological process that allows epithelial cells to undergo biochemical changes that enable it to assume the phenotype of a mesenchymal cell. Phenotypic changes include ability to migrate, invasiveness, resistance to apoptosis, and increased production of extracellular matrix components.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.