Histone Methylation

Histone methylation is the process of transferring methyl groups to amino acids of histone proteins. When histones are methylated transcription of genes can be repressed or activated. Dysregulation of histones has been implicated in various types of disease including cancers.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.