Eukaryotic initiation factor 4 (eIF4) is important in translation initiation. eIF4 is a cap-binding protein that works with eIF4G (a scaffolding protein) to bind to mRNA. This binding is important for the recruitment of ribosomes and translation initiation.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.