Ubiquitin Proteasome

The ubiquitin-proteasome system (UPS) is a principal pathway involved in clearing short-lived, damaged, and misfolded proteins from cells via the proteasome. It is one of the major destruction ways to control protein activity.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.