Basic Information

Strain Name B6/JGpt-Apoeem1Cd82/Gpt
Strain Number T001458
Official Symbol Apoe
Official Full Name apolipoprotein E
Also Known As AI255918,ApoE
NCBI Number 11816
Research Areas Muscle respiratory system , adipose tissue , Cell Proliferation , Cell death , Cytoskeleton , DNA transcription , digestive/alimentary system , Protein metabolism , liver/biliary system , renal/urinary system , Physiological system , endocrine/exocrine glands , homeostasis/metabolism , behavior/neurological , cell differentiation , Cell biology , Molecular biology , Metabolic research , Developmental Biology , cellular , growth/size/body , hematopoietic system , mortality/aging , Cell localization , Lipid Metabolism , Cytoplasmic vesicle , immune system , endoplasmic reticulum , endosome , Golgi apparatus , cell nucleus , cytomembrane , Organelles membrane , synapse , integument , Regulation of enzyme activity , cardiovascular system , Lipid binding protein , transporter , nervous system , Signal Transduction , skeleton , vision/eye , hearing/ear , taste/olfaction
Strain Background C57BL/6JGpt
Modification Type Knockout (KO)
Genotyping Protocols -
Related Links NCBI: 11816
View Quote Cart

Product Status

Inventory Status Live , Cryopreserved
Sale Status Available for Distribution
Health Status Specific pathogen free (SPF)

Published Literature

Name of Document URL
Nicotine modulates CTSS (cathepsin S) synthesis and secretion through regulating the autophagy-lysosomal machinery in atherosclerosis https://doi.org/10.1161/ATVBAHA.120.314053
LncRNA NORAD promotes vascular endothelial cell injury and atherosclerosis through suppressing VEGF gene transcription via enhancing H3K9 deacetylation by recruiting HDAC6 https://doi.org/10.3389/fcell.2021.701628
Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway https://doi.org/10.3390/antiox10060916
Targeting macrophage liver X receptors by hydrogel‐encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis https://doi.org/10.1111/bph.15387
BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis https://doi.org/10.1016/j.redox.2021.101979
BTK Promotes Atherosclerosis by Regulating Oxidative Stress, Mitochondrial Injury, and ER Stress of Macrophages https://doi.org/10.1155/2021/9972413
ZBTB20 Positively Regulates Oxidative Stress, Mitochondrial Fission, and Inflammatory Responses of ox-LDL-Induced Macrophages in Atherosclerosis https://doi.org/10.1155/2021/5590855
circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis https://doi.org/10.3389/fcell.2021.652032
ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway https://www.thno.org/v11p1129.htm
Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology https://doi.org/10.1111/imm.13401
Ablation of Plasma Prekallikrein Decreases LDL Cholesterol by Stabilizing LDL Receptor and Protects against Atherosclerosis https://doi.org/10.1161/CIRCULATIONAHA.121.056491
Qing-Xin-Jie-Yu Granule alleviates atherosclerosis by reshaping gut microbiota and metabolic homeostasis of ApoE-/- mice https://doi.org/10.1016/j.phymed.2022.154220
Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production https://doi.org/10.1016/j.cellsig.2022.110419

Navigation

Strain Type

Load More

Research Area

Load More

Breeding Type

Sale Status