Basic Information

Strain Name B6/JGpt-Apoeem1Cd82/Gpt
Strain Number T001458
Official Symbol Apoe
Official Full Name apolipoprotein E
Also Known As AI255918,ApoE
NCBI Number 11816
Research Areas Muscle respiratory system , adipose tissue , Cell Proliferation , Cell death , Cytoskeleton , DNA transcription , digestive/alimentary system , Protein metabolism , liver/biliary system , renal/urinary system , Physiological system , endocrine/exocrine glands , homeostasis/metabolism , behavior/neurological , cell differentiation , Cell biology , Molecular biology , Metabolic research , Developmental Biology , cellular , growth/size/body , hematopoietic system , mortality/aging , Cell localization , Lipid Metabolism , Cytoplasmic vesicle , immune system , endoplasmic reticulum , endosome , Golgi apparatus , cell nucleus , cytomembrane , Organelles membrane , synapse , integument , Regulation of enzyme activity , cardiovascular system , Lipid binding protein , transporter , nervous system , Signal Transduction , skeleton , vision/eye , hearing/ear , taste/olfaction
Strain Background C57BL/6JGpt
Modification Type Knockout (KO)
Genotyping Protocols -
Related Links NCBI: 11816
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Product Status

Inventory Status Live , Cryopreserved
Sale Status Available for Distribution
Health Status Specific pathogen free (SPF)

Published Literature

Name of Document URL
Nicotine modulates CTSS (cathepsin S) synthesis and secretion through regulating the autophagy-lysosomal machinery in atherosclerosis
LncRNA NORAD promotes vascular endothelial cell injury and atherosclerosis through suppressing VEGF gene transcription via enhancing H3K9 deacetylation by recruiting HDAC6
Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway
Targeting macrophage liver X receptors by hydrogel‐encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis
BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis
BTK Promotes Atherosclerosis by Regulating Oxidative Stress, Mitochondrial Injury, and ER Stress of Macrophages
ZBTB20 Positively Regulates Oxidative Stress, Mitochondrial Fission, and Inflammatory Responses of ox-LDL-Induced Macrophages in Atherosclerosis
circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis
ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway
Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology
Ablation of Plasma Prekallikrein Decreases LDL Cholesterol by Stabilizing LDL Receptor and Protects against Atherosclerosis
Qing-Xin-Jie-Yu Granule alleviates atherosclerosis by reshaping gut microbiota and metabolic homeostasis of ApoE-/- mice
Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production


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