COVID19 Portfolio hACE2 Order hACE2 Info

T037659 [B6-hACE2, full-length human]

Strain Name: B6/JGpt-Ace2em1Cin(hACE2)/Gpt

Strain Type: KI (Cas9)

Strain ID: T037059

Background: C57BL/6JGpt

Gene Symbol: ACE2; Ace2

Alias: ACEH; 2010305L05Rik

NCBI Gene ID: 59272, 70008
Strain Strategy
Genotyping Protocol

Product Status: Live, Cryopreserved

Availability: Live mice 50% off, ready to ship from Boston Inquire

Health Status: Specific pathogen free (SPF)

Reference

  1. Qiao, J. et al. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model.  Science. 371 (6536): 1374-1378. (2021).  DOI: 10.1126/science.abf1611

T037630 [B6-hACE2, chimeric human-mouse]

Strain Name: B6/JGpt-Ace2em1Cin(hACE2-stop)/Gpt

Strain Type: KI (Cas9)

Strain ID: T037630

Background: C57BL/6JGpt

Gene Symbol: ACE2; Ace2

Alias: ACEH; 2010305L05Rik

NCBI Gene ID: 59272, 70008
Strain Strategy
Genotyping Protocol

Product Status: Live, Cryopreserved

Availability: Available for distribution

Health Status: Specific pathogen free (SPF)

Reference

  1. Ma, X. et al. Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses. Immunity. 53 (6): P1315-1330.E9. (2020).  https://doi.org/10.1016/j.immuni.2020.11.015
  2. Alitongbieke, G. et al. Effect of β-chitosan on the binding interaction between SARS-CoV-2 S-RBD and ACE2. BioRxiv. (2020).  https://doi.org/10.1101/2020.07.31.229781

T037657 [B6-H11-K18-hACE2, full-length human]

Strain Name: B6/JGpt-H11em1Cin(K18-hACE2)/Gpt

Strain Type: KI (Cas9)

Strain ID: T037657

Background: C57BL/6JGpt

Gene Symbol: ACE2

Alias: ACEH

NCBI Gene ID: 59272
Strain Strategy
Genotyping Protocol

Product Status: Cryopreserved

Availability: Available for distribution

Health Status: Specific pathogen free (SPF)

Reference

  1. Zhang, S., Liu, Y., Wang, X. et al. SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19. J Hematol. Oncol 13, 120 (2020).  https://doi.org/10.1186/s13045-020-00954-7
  2. Bai, L. et al. Co-infection of influenza A virus enhances SARS-CoV-2 infectivity. BioRxiv. (2020).  https://doi.org/10.1101/2020.10.14.335893
  3. Bai, L. et al. Coinfection with influenza A virus enhances SARS-CoV-2 infectivity. Cell Res 31, 395–403 (2021). https://doi.org/10.1038/s41422-021-00473-1

T037915 [BALB/c-hACE2, full-length human]

Strain Name: BALB/cJGpt-Ace2em1Cin(hACE2)/Gpt

Strain Type: KI (Cas9)

Strain ID: T037915

Background: BALB/cJGpt

Gene Symbol: ACE2; Ace2

Alias: ACEH; 2010305L05Rik

NCBI Gene ID: 59272, 70008
Strain Strategy
Genotyping Protocol

Product Status: Cryopreserved

Availability: Live mice 50% off, ready to ship from Boston Inquire

Health Status: Specific pathogen free (SPF)

Reference

T037766 [NCG-hACE2, full-length human]

Strain Name: NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22Ace2em1Cin(hACE2)/Gpt

Strain Type: KI (Cas9)

Strain ID: T037766

Background: NCG (NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22/Gpt)

Gene Symbol: Ace2; ACE2

Alias: 2010305L05Rik; ACEH

NCBI Gene ID: 70008, 59272
Strain Strategy
Genotyping Protocol

Product Status: Cryopreserved

Availability: Available for distribution

Health Status: Specific pathogen free (SPF)

Reference